Discovery develops processes that uncover underlying mechanisms contributing
to human disease and identifying potential drug candidates. The goal of these
efforts is to discover novel therapies to combat disease and to improve and
enhance the quality of life.
Therapeutic Areas:
Cardiovascular Disease
Millions of Americans have been diagnosed with some
form of cardiovascular disease. Fundamental breakthroughs in
medical research have allowed for the understanding of certain disease processes.
New information, such as the sequencing of the human genome, has served to
create a foundation for associating genes correlated with disease and molecular-based
drug discovery programs. Technological advances in structural research,
genetic analysis and cell signaling have allowed us to reduce
human disease to a process that can translate to novel and vital drugs. Our
multidisciplinary cardiovascular research teams utilize all elements of modern
research to aid in the discovery of new treatments for heart failure, hypertension
(also known as high blood pressure), and atherosclerosis (the hardening of
the arteries).
Immunology and Inflammation
Our immunology and inflammation researchers
are working with cutting edge technology to help find new
treatments for chronic immune and inflammatory diseases such as rheumatoid
arthritis, multiple sclerosis and psoriasis. Our goal is to develop new and
improved therapies that halt or slow the progression of these diseases, thereby
improving the daily quality of life for patients. With the advent of
new technologies that allow for the investigation of human disease at the
molecular level, we employ multiple model systems to address key mechanisms
that underly how inflammatory processes progress in order to develop novel
therapies for disease treatment.